Top Sloan Kettering Cancer Doctor Resigns After Failing to Disclose Millions of Dollars in Payments from Health Care Companies. Michael Towner, Iconic Legacy

Dr. José Baselga, the chief medical officer of Memorial Sloan Kettering Cancer Center, has resigned amid reports that he failed to disclose millions of dollars in payments from health care companies in dozens of research articles.

​The revelations about Dr. Baselga’s disclosure lapses, reported by The New York Times, have rocked Memorial Sloan Kettering, one of the nation’s leading cancer centers, in recent days. Its top executives scrambled to contain the fallout, including urgent meetings of physician leaders and the executive committee of its board of directors.

In his resignation letter, Dr. Baselga, who also served as the physician-in-chief, said he feared that the matter would be a distraction from his role overseeing clinical care and that he had been “extremely proud” to work at Memorial Sloan Kettering.
“It is my hope that this situation will inspire a doubling down on transparency in our field,” he said, adding that he hoped the medical community would work together to develop a more standardized system for reporting industry ties.

In an email sent to the staff Thursday evening, Dr. Craig B. Thompson, the hospital’s chief executive, said that Dr. Baselga had made “numerous” contributions to Memorial Sloan Kettering, patients and cancer treatment. Dr. Lisa DeAngelis, the chairwoman of the neurology department, will take over as acting physician-in-chief until Dr. Baselga’s successor is hired.

The Times found that Dr. Baselga had failed to report any industry ties in 60 percent of the nearly 180 papers he had published since 2013. That figure increased each year — he did not disclose any relationships in 87 percent of the journal articles that he co-wrote last year.

In an interview and later statement, Dr. Baselga said he planned to correct his conflict-of-interest disclosures in 17 journal articles, including in The New England Journal and The Lancet. But he contended that in dozens of other cases, no disclosure was required because the topics of the articles had little financial implication. He also said his failed disclosures were unintentional and should not reflect on the value of the research he conducted.

Medical journals and professional societies have imposed stricter rules about reporting relationships to industry after a series of scandals a decade ago in which prominent physicians failed to disclose payments from drug companies. But medical journals have said they don’t routinely fact-check authors’ disclosures, and much is left to the honor system.

Dr. Baselga received nearly $3.5 million in payments from drug, medical equipment and diagnostic companies from August 2013 through 2017, according to Open Payments, a federal database that tracks payments to physicians from health care companies. Most of that amount, about $3 million, involved a payment from Genentech for Dr. Baselga’s ownership interest in a company it acquired, Seragon Pharmaceuticals, in 2014.

But the $3.5 million in the Open Payments database does not include payments from companies that don’t have products approved by the Food and Drug Administration. Such companies are not required to report their payments under federal law.

For instance, Infinity Pharmaceuticals, a start-up with no approved drug, paid Dr. Baselga nearly $250,000 in cash and stock options for serving on its board from 2015 to 2017. He declined to disclose how much he received from such companies.

Dr. Baselga was one of the highest-paid staff members at Memorial Sloan Kettering, earning more than $1.5 million in 2016, the most recent year for which the nonprofit’s financial filings are available.

​Michael Towner

---